9 major effects of grape seeds [2024] Some taboos cannot be ignored!

Grape seed, English is Grape seed extract It is a high-antioxidant dietary supplement, which has a lot of benefits to the human body.

More and more people who are pursuing healthy began to recognize the benefits of grape seeds.What are the effective substances contained in grape seeds?What are the benefits of human body?

Directory of this article

What is grape seed?
What are the effects of grape seeds?
How to eat grape seeds?
Who can consider replenishing grape seeds?
Can grape seed supplements be used every day?
When is the grape seeds taken?
What are the side effects of grape seeds?
Can grape seeds be taken with other vitamins?
Can grape seeds and calcium and magnesium supplements be taken together?
Grape seed capsule recommendation
references
common problem

What is grape seed?

Grape seed, English name Grape SEED, as a daily dietary supplement, takes grape seed extract (Grape Seed Extract), referred to as GSE.

Grape seed extract is a dietary supplement.By removing grape skin and pulp, the nutrients that are extracted from the grape seeds and shattered after the drying of grape seeds.

Grape seeds are rich in various antioxidants, including Phenolic Acids, Flavonoids, and oligomeric Proanthocyanidin (OPC).

In fact, grape seeds are one of the source of the original flowers.

OPC has been proven to effectively remove free radicals in the body and prevent oxidative damage in various body, including various cardiovascular problems, brain function degradation problems, can maintain the health of internal organs such as kidney and liver, etc.Delay the spread of cancer in the body^{[1] [2]}Essence

What are the effects of grape seeds?

The most important effect of grape seeds is antioxidant, and also has multiple effects such as protecting the heart, reducing blood pressure, and protecting the liver:

1.Antioxidant and anti-aging

Grape seeds are famous anti-aging ingredients in Europe.Whether it is the grape seed capsules, grape seed oil, or various types of grape seed skin care products, many brands have launched their own grape seed series, such as the French Opi Li in France Caudalie,, German M.asam And Spain’s Reveradox wait.

Through the antioxidant ingredients in grape seeds, the aging phenomenon that the free radical oxidation brings to the body from the inside and outside, such as dry skin, wrinkles, and dull complexion.Sope at the European beauty care industry.

2.Protect heart health

Low-density lipoprotein cholesterol is a harmful protein cholesterol to the human body.The increase in the content of its blood will increase the probability of cardiology, as well as the probability of the formation of fatty plaques in the inheritance-shaped or arteries.^[3]Essence

A comparison experiment shows that when 8 healthy people are mentioning high-fat meals, one group is taken for 300 mg of grape seeds, and the other is not taken.After being tested, the content of low density lipoprotein cholesterol in the body in the body of grape seeds was effectively controlled, and the control group of not taking grape seeds increased by 150%^[4]Essence

In another study, 61 healthy adults found that low-density lipoprotein cholesterol after taking 400 mg of grape seeds was reduced by 13.9%^[5]Essence

Another study of 87 patients undergoing cardiac surgery found that taking 400 mg of grape seeds one day before surgery can significantly reduce oxidation stress in the body.Therefore, it is inferred that grape seeds may prevent further heart damage from further heart injury^[6]Essence

3.Reduce blood pressure

Many clinical experiments have proved that taking grape seeds can effectively relieve hypertension.

There were 16 research on 810 people with high blood pressure or risk of hypertension.After summing up the data, it was found that taking 100-2,000 mg of grape seeds every day can effectively reduce systolic and diastolic blood pressure, that is, the highest pressure and minimum pressure.Can be reduced by an average of 6.08 mm Hg and 2.8 mm Hg.The best effect on people under 50 years of obesity or metabolic disorders^[7]Essence

4.Promote blood circulation

Some studies have shown that grape seeds can promote blood circulation.

In a 8 -week study of 17 healthy women after menopause, taking 400 mg of grape seeds has the effect of diluted blood, which can reduce the risk of thrombosis^[8]Essence

Another comparison research on 8 healthy and young women showed that sitting quietly after taking 400 mg of grape seeds for 6 hours immediately, compared with the grape seed group, the legs of the group with grape seeds were swollen and edema.%.Another control group is to take 133 mg grape seeds daily within 14 days.After sitting for 6 hours, the leg swelling is reduced by 40%^[9]Essence

5.Improve the level of osteoprotein and bone strength

There are enough positive correlations of osteoplastin levels and bone strength, and sufficient flavonoid content can optimize the synthesis of bone collagen and the strength of the bones.Improve bone health.

Animal experiments show that after adding grape seeds, whether the diet is low calcium, standard or high calcium, can increase bone density, mineral content and bone strength^[10]Essence

6.Delay the onset of neurodegenerative diseases

The antioxidant and anti-inflammatory characteristics of flavonoids can delay or reduce the onset of diseases such as Alzheimer’s disease.A 12 -week study of 111 healthy elderly people found that taking 150 mg of grape seeds per dayCan improve attention, language, instant and delay memory^[11]Essence

7.Improve kidney function

The kidneys are very vulnerable to oxidative damage, and this damage is usually irreversible.Some studies have proved that taking grape seeds can slow down the kidney oxidative damage and improve its function by reducing oxidation stress and inflammatory damage.In a clinical study, 23 patients diagnosed with chronic renal failure were divided into test groups and placebo groups.The test group took 2 grams of grape seeds per day, lasting for 6 months, and then compared with the placebo group, take it, take itThe urinary protein of the grape seeds reduced by 3%, and the kidney filtration rate increased by 9%.This means that the test group has improved the urine function of the kidney filtration compared to the placebo group^[12]Essence

8.Protect the liver

Hepatase alanine aminotransferase -Alanine Aminotransferase (ALT) is a key indicator of hepatic toxicity, which refers to the health of the liver.The higher the AlT indicator, the more serious the liver damage.In a study of 15 patients with non-alcoholic fatty liver diseases with non-alcoholic fatty liver diseases — Non-Alcoholic Fatty Liver Disease and subsequent ALT levels, it was found that during the 3-month grape seeds, the ALT indicator was monitored every month.And compare the results with the control group of 2 grams of vitamin C every day.After 3 months, the ALT of the grape seed group dropped by 46%, while the vitamin C group almost did not change^[13]Essence

9.It may reduce the risk of cancer

Data show that a large number of antioxidants, such as flavonoids and primary flowers, are related to the reduction of various cancers risks^[14]EssenceStudies conducted in the laboratory environment show that the antioxidant activity of grape seeds can inhibit the diffusion of cancer cells such as human pancreatic cancer cells, colorectal cancer cells, etc.^{[15] [16]}Essence

How to eat grape seeds?

Grape seed dietary supplements are usually sold as capsules or powder.Without the doctor’s clear suggestion, they can be taken according to the taking guidelines provided by the manufacturer, but they should not take different types of grape seed dietary supplements at the same time to avoid taking it.Donestion caused by excessive amount.

Taking grape seeds and vitamin C may increase blood pressure.If you have high blood pressure, you should avoid taking them at the same time.

Grape seeds and lactic acid bacteria should also be avoided at the same time as much as possible, because grape seeds may slow down the growth of beneficial bacteria and reduce the beneficial activity of lactobacillus^[17]Essence

The impact of grape seed dietary supplements on infants and pregnant women has no clear research, but it is not recommended to take such people.^[18]Essence

Who can consider replenishing grape seeds?

It can be seen from the benefits of grape seeds to the human body that people with cardiovascular problems or cardiovascular problems can take grape seed dietary supplements to improve the operating status of the overall cardiovascular circulation system.

In addition, for people who want to eliminate free radicals to act as anti-aging, they can also take grape seed dietary supplements rich in antioxidants such as flavonoids and primary flowers.

Can grape seed supplements be used every day?

As long as there is no adverse reaction after taking, all people can take grape seed dietary supplements every day to improve the internal circulation and achieve antioxidant effects.For pregnant women and lactating women, please do not take it, you should consult your doctor.

When is the grape seeds taken?

Because grape seed dietary supplements do not contain fatty substances, it is not necessary to take it with oil foods.

At the same time, there is no adverse reaction report for stomach discomfort after taking it.Therefore, it is recommended to take it under an empty stomach to reduce the absorption rate when digesting with other foods.

Of course, if you have an empty stomach discomfort, you will not occur with other foods, and this will not happen when taking it with other foods, then there is no problem with taking it with meals.

What are the side effects of grape seeds?

Grape seeds are usually considered safe and have few side effects.Some studies need to take the dose of 300-800 mg, which lasts 8-16 weeks.There is no bad phenomenon report.It has good tolerance^[7]Essence

However, grape seeds have the effects of lowering blood pressure, dilution of blood and increasing blood flow.Therefore, people with blood dilution or blood pressure drugs are recommended to take it cautiously to avoid excessive effect^{[7] [8] [9]}Essence

Of course, allergies are still possible.If you are taken after taking urticaria, dyspnea, facial, lips, tongue, or throat swelling, etc., you should stop taking it immediately.

Finally, if you are using any of the following drugs, please don’t take grape seed dietary supplements without a doctor’s suggestion^[17]The

Riluzol, Clopidogrel, Cyclobenzaprine, Estradiol, Flutamide, Naproxen, and ONDANSETRON, Ropinirole, Tacrine, Warfarin;
Some antidepressants-amitriptyline, Clomipramine, Desipramine, Fluvoxamine, ImiPramine, and to Alene Forest(nortriptyline);
Some asthma drugs -Theophylline Zileuton;
Some hearts or blood pressure drugs -Mexiletine, Propafenone, Propranolol, Verapamil; Verapamil;
Some drugs that treat anxiety or mental illnesses-chlordiazepoxide, Clozapine, DiazePam, Haloperidol, mirtazapine, and octopamentalOlanzapine.

Can grape seeds be taken with other vitamins?

At present, it is clear that people with high blood pressure may have adverse reactions if you take grape seeds and vitamin C together.For other vitamins, you can consult professional medical personnel before taking it.^[17]Essence

Can grape seeds and calcium and magnesium supplements be taken together?

[8] SONIA FSHENOY, Carl L Keen, SWATI KALGAONKAR, JOHN A POLAGRUTO.Effects of Grape Seed Extract Consumption on Placelet Function in PostMenopausal Women.Thromb res.2007.

[9] Atsushi Sano, Shoichi Tokutake, Akihiko SEO.Pronthocyanidin-Rich Grape Seed Extract Reduces Leg Swelling in Healthy Women During Prolonged Sitting J sci Food Agric.2013.

[10] N Yahara, I Tofani, K Maki, K Kojima, Y Kojima, M Kimura.Mechanical Assessment of Effects of Grape Seed ProAnthocyanidins Extract on TIBIAL BONE DIAPHYSIS in Rats J Musculoskelet Neuronal Interact.2005 jun.

[11] GIOACCHINO CAAPAI, Francesco Bonina, Andrea Bonina, Luisa Rizza, Carmen Mannucci, Vincenzo Arcoraci, Germana Laganà, ANGELA Alibrandi, Concepta Pollicino, Santi, Santi Inferrera, umberto alecci.A randomized, double-black, Clinical TRIAL On Effects of a Vitis Vinifra Extract on Cognction in Healthy Older Adults.FRONT PHARMACOL.2017 Oct.

[12] Khaoula Turki, Kamel Charradi, Habib Boukhalfa, Monia Belhaj, Ferid Limam, EZZEDINE AOUANI.Grape SEED POWER IMPROVES RENAL FAILURE of Chronic Kidney Disease Patients.Excli j.2016 jun.

[13] Manouchehr Khoshbaten, Akbar Aliasgarzadeh, Koorosh Masnadi, Sara Farhang, Mohammad K Tarzamani, Hosain Babaei, Javad Kiani, Maryam Zaare, Farzad Naja fipoor.Grape Seed Extract to Improve Liver Function in Patients with Nonalcoholic Fatty Liver Change.Saudi J Gastroenterol.Jul-sep 2010.

[14] Debasis Bagchi, Anand Swaroop, Harry G Preuss, Manashi Bagchi.Free Radical Scavenginging, Antioxidant and CANCER Chemoprevent by Grape Seed Proanthocyanidin: An Overview.Mutat res.2014 OCT.

[15] Molly Derry, Komal Raina, Rajesh Agarwal, and Chapla Agarwal.Differential Efffects of Grape Seed Extract Against Human Colorectal Cancer Cell Lines: The Intricate ROLE of Death Receptors and Mitochondria PMC 2014 jun.

[16] RAM PRASAD, Santosh K Katiyar.Grape SEED ProAnthocyanidins Inchibit Migration Potential of Pancreatic CAMOTINGYYMAL-TO-EPITHELILILILILILILILILILILILILILILILILILILILILILILALA.Cancer lett.2013 jun.

[17] Grape seed Drugs.com

[18] The health benefits of grape seed extract, Vrywellhealth.com

common problem

Question 1: What is grape seed English?

Grape seed English is Grape SEED EXTRACT.It is a high-antioxidant dietary supplement, which has many benefits to the human body.
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Question 2: What are the effects of grape seeds?

Grape seeds have at least nine major effects:
1.Antioxidant and anti-aging
2.Protect heart health
3.Reduce blood pressure
See More